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Information for Authors
American Journal of Neurodegenerative Disease (AJND, ISSN: 2165-591X) is an open access online journal
dedicated to rapid publication of basic and clinical research findings in neurodegenerative diseases including, but not
limited to Alzheimer’s Disease (AD), Parkinson’s Disease (PD), corticobasal degeneration, progressive supranuclear
palsy (PSP), Pick's disease, and frontotemporal dementia (FTD), etc. The scope of AJND encompasses all areas of
neurodegenerative disease. AJND welcomes original and review articles on both clinical investigation and basic
research. Occasionally, special topic issues, short communications, editorials, and invited perspectives will also be
published. Manuscripts, including figures and tables, must be original and not under consideration by another journal.
SUBMISSION OF MANUSCRIPT
General Policy
All manuscripts are submitted with the understanding that they have not been published elsewhere (except in the form
of an abstract or as part of a published lecture or thesis) and are not currently under consideration for publication by
another journal. It is the responsibility of the corresponding author to ensure that all authors have contributed to, read
and approved the final manuscript for submission. The authors should keep a copy of manuscript submitted in case of
revision, rejection, loss or damage. Receipt of manuscript will be acknowledged and a decision regarding acceptance
made as soon as possible. Accepted manuscripts may be subject to editorial revision without notice.
Peer Review Policy
All manuscripts are subject to peer review and are expected to meet the rigorous standards of academic excellence.
Authors should provide 4 potential peer reviewers with detailed contact information including e-mail address. Authors
may also nominate 2 peers that they request are not sent the article for peer review for conflicts of interest or other
appropriate reasons – in such instances some reasonable justification must be given. These should be experts in
their field of study, who will be able to provide an objective assessment of the manuscript. If not provided, potential
reviewers will be identified by their publication record or recommended by the Editorial Board members.
Copyright Policy
By submitting a manuscript to AJND, all authors agree that all copyrights of all materials included in the submitted
manuscript will be exclusively transferred to the publisher - e-Century Publishing Corporation once the manuscript is
accepted.
Once the paper is published, the copyright will be released by the publisher under the “Creative Commons Attribution
Noncommercial License”, enabling the unrestricted non-commercial use, distribution, and reproduction of the
published article in any medium, provided that the original work is properly cited. If the manuscript contains a figure or
table reproduced from a book or another journal article, the authors should obtain permission from the copyright holder
before submitting the manuscript, and be fully responsible for any legal and/or financial consequences if such
permissions are not obtained.
All PDF, XML and html files for all articles published in this journal are the property of the publisher, e-Century
Publishing Corporation (www.e-Century.org). Authors and readers are granted the right to freely use these files for all
academic purposes. By publishing paper in this journal, the authors grant the permanent right to the publisher to use
any articles published in this journal without any restriction including, but not limited to academic and/or commercial
purposes. If you are interested in using PDF, html, XML files or any art works published in this journal for any
commercial purposes, please contact the publisher at business@e-century.org.
Use of Human Subjects/Human Tissue and/or Animal Policy
Experiments involving human subjects should be done in accordance with the relevant ethical and legal standards
established and accepted by their host institution or in accordance with the Helsinki Declaration of 1975, or the
Guidelines of Office for Human Research Protections (OHRP) Human Subject Protections or equivalent. For studies
that involved human subjects, when informed consent has been obtained it should be indicated in the manuscript.
Experiments involving animals should follow the appropriate institution or the National Research Council Guide for the
care and use of laboratory animals.
Units and Abbreviations
System International (SI) units should be used for all measurements. All abbreviations should be explicitly defined at
their first occurrence except for those internationally acceptable. Abbreviations used in the genetic association reports
will need to follow the conventions detailed in the specific information requirements for genetic association reports. Any
articles that involve the description of enzymes will require the inclusion of the appropriate EC (Enzyme Commission)
number as recommended by the Nomenclature Committee of the International Union of Biochemistry and Molecular
Biology (IUBMB).
Disclaimer
While the advice and information in the article are believed to be true and accurate on the date of its going to press,
neither the authors nor the editors can accept any legal responsibilities for any errors or omissions that may be made.
The publication makes no warranty, expressed or implied, with respect to the materials contained within.
PREPARATION OF MANUSCRIPT
All manuscripts should be written in standard grammatical English using computer software (Franklin Gothic Book
normal font, size 12, with single spacing between lines) and should be saved as single DOC (Word) file. Main
Research Articles and Brief Communications will follow a similar format as outlined below while Review Articles will
follow a variation on this (see below).
Main Research Articles are defined as being a substantial novel research study discussing the investigation of a clear
hypothesis or research question with appropriate methodologies (the use of more than one approach is encouraged)
and adequately powered studies and sample sizes. Noting the relevant sections (see below) there is no word limit on
manuscripts of this type except for the Abstract which should be a single unreferenced paragraph and no more than
350 words. There are no limits on the number of display items (tables and/or figures) although authors should try to be
concise and only include the most pertinent information. There are no supplementary tables or figures and every effort
should be made to include these in the main manuscript or alternatively reference should be made in the appropriate
locations of the manuscripts that such information will be available on request from the
corresponding authors. There is no limit on the number of references.
Brief Communications are a format that accommodates the reporting of high quality completed smaller scale studies.
This format is not for the reporting of preliminary or incomplete findings and the review process is equally rigorous as
that for Main Articles. The sections of a Brief Communication follow those of Main Articles (see below) and there should
not be additional sub-headings within these sections.
Review articles have a flexible format, are not of restricted length or reference number. Submissions of reviews must
follow that of Main Research Articles (see below) with the exception that appropriate headings be included for the main
text of the manuscript.
Layout requirements for submissions of Main Research Articles or Brief Communications:
1. cover letter
2. title page
3. abstract and keywords
4. main text
5. acknowledgements, if any
6 Declaration of conflicts of interest, if any
7. References
8. tables, if any
9. figure legends, if any
10. figures, if any
Cover Letter
The cover letter should include name, degree, address, telephone, fax and email of the corresponding author. A
statement that all authors have contributed to, read and approved the final manuscript for submission should be
included if there are multiple authors. Any editorial or financial conflict of interest (e.g., consultancy, stock ownership,
equity interests, patent or licensing agreements) should be clearly disclosed in the cover letter. The disclosure
statement must be submitted upon the acceptance. The cover letter should also be used to provide up the relevant
details of 4 potential reviewers and 2 non-reviewers for your manuscript giving appropriate explanations for the latter.
Finally, if this submission is following the solicitation or invitation of an Editorial Board member please state by whom.
Title Page
1. a concise title;
2. first name, middle initial, and last name of each author;
3. name of the department and institutional affiliation of each author.
4. the email address of each author.(*)
5. a running title.
(*) AJND will only use the email address of the designated corresponding author in the final published manuscript but
will use all email addresses supplied to copy in all authors as additional email respondents to the correspondences
we routinely send to acknowledge receipt of manuscripts, and final decisions made on submitted manuscripts. AJND
would also like, unless otherwise directed in the manuscript covering letter, to use these contact details to announce
the contents lists of future issues of AJND and its sister journals! At no stage will AJND sell such email lists to parties
external to the e-Century Publishing Corporation.
Abstract and Key Words
Abstract should not exceed 350 words that concisely summarize the study’s purpose, significant findings and
conclusions. Include up to 10 key words or phrases at the end of the abstract.
Main Text
The main text should include Introduction, Materials and Methods, Results and Discussion. The Introduction should be
succinct, clearly stating the purpose and rationale of the study. In Materials and Methods, the procedures should be
described in sufficient detail to allow duplication by an independent observer. Results and Discussion should be
divided. They should be written concisely and logically with emphasis on novel findings and minimal repetition of text.
For genetic association reports refer to specific information requirements.
Acknowledgements
All acknowledgements (if any) should be included at the end of the main text before references and may include grant
and administrative support.
References (Please download EndNote X Style or Reference Manager Output Style for AJND)
Reference published in AJND should begin on a new page, be single-spaced and numbered in order of citation in the
text, including citations in tables and figure legends. Complete author citation is required (use of "et al" is not
acceptable). References should conform to the style of the Journal. Examples follow:
Journals: [1] Yin M, Hu Z, Tan D, Ajani JA, Wei Q. Molecular epidemiology of genetic susceptibility to gastric cancer:
focus on single nucleotide polymorphisms in gastric carcinogenesis. Am J Transl Res 2009;1:44-54.
Books: Fishman AP: Pulmonary Hypertension and Cor Pulmonale. Pulmonary Diseases and Disorders. Edited by
Fishman AP. New York, McGraw-Hill, 1988, pp. 999-1048
Web sites: Cite in text only using the appropriate URL. It is the author’s responsibility at the time of submission and
subsequent publication that the website address is relevant and functional.
In press: To be used only for papers accepted for publication. Cite as for journal with (in press) in place of volume and
page numbers.
Personal Communications: to be used very sparingly and in the context of no more than one sentence of associated
text.
Submitted papers/unpublished data: Cite in text only.
Tables
All tables should be created with Microsoft Word Insert Table function, single spacing between rows and cited
consecutively in the main text by Arabic numbers (Table 1, Table 2, etc) and submitted as editable Word file. Include
each table with a descriptive title on a separate page after the references. Provide explanations for any nonstandard
abbreviations in footnotes to the table.
All tables should be included in the Word File as the part of the complete manuscript after bibliography. Tables in
image or other formats are not acceptable. Authors are encouraged to split extremely large tables into multiple smaller
ones to facilitate publication and easiness to readers.
Figure Legends
Figure legends including figure number, a short title and detailed description should be embedded at the end of text
file.
Figures
All figures should be cited consecutively in the main text by Arabic numbers (Figure 1, Figure 2, etc). All figures must be
submitted in TIFF or JPEG format as separate files labeled with the corresponding numbers. Photographs of a person
should render them unidentifiable or include their written permission. Any figures involving Copyright issues should
conform to the Copyright policy.
Publication Fees
American Journal of Neurodegenerative Disease is an open access journal which provides instant, worldwide and
barrier-free access to the full-text of all published articles. Publication charges allow the publisher to make the
published material available for free to all interested online readers.
The Publishing fee is $980 per article. This will be billed to the corresponding author. There is no extra charge for color
figures. Authors who do not have appropriate funds from developing countries can apply to have the reduced fee by
submitting a letter signed by the departmental chair to state such a fact. Editorial decisions are not contingent upon the
ability to pay publication charges.
American Journal of Neurodegenerative Disease (AJND, ISSN: 2165-591X) is an open access online journal
dedicated to rapid publication of basic and clinical research findings in neurodegenerative diseases including, but not
limited to Alzheimer’s Disease (AD), Parkinson’s Disease (PD), corticobasal degeneration, progressive supranuclear
palsy (PSP), Pick's disease, and frontotemporal dementia (FTD), etc. The scope of AJND encompasses all areas of
neurodegenerative disease. AJND welcomes original and review articles on both clinical investigation and basic
research. Occasionally, special topic issues, short communications, editorials, and invited perspectives will also be
published. Manuscripts, including figures and tables, must be original and not under consideration by another journal.
SUBMISSION OF MANUSCRIPT
General Policy
All manuscripts are submitted with the understanding that they have not been published elsewhere (except in the form
of an abstract or as part of a published lecture or thesis) and are not currently under consideration for publication by
another journal. It is the responsibility of the corresponding author to ensure that all authors have contributed to, read
and approved the final manuscript for submission. The authors should keep a copy of manuscript submitted in case of
revision, rejection, loss or damage. Receipt of manuscript will be acknowledged and a decision regarding acceptance
made as soon as possible. Accepted manuscripts may be subject to editorial revision without notice.
Peer Review Policy
All manuscripts are subject to peer review and are expected to meet the rigorous standards of academic excellence.
Authors should provide 4 potential peer reviewers with detailed contact information including e-mail address. Authors
may also nominate 2 peers that they request are not sent the article for peer review for conflicts of interest or other
appropriate reasons – in such instances some reasonable justification must be given. These should be experts in
their field of study, who will be able to provide an objective assessment of the manuscript. If not provided, potential
reviewers will be identified by their publication record or recommended by the Editorial Board members.
Copyright Policy
By submitting a manuscript to AJND, all authors agree that all copyrights of all materials included in the submitted
manuscript will be exclusively transferred to the publisher - e-Century Publishing Corporation once the manuscript is
accepted.
Once the paper is published, the copyright will be released by the publisher under the “Creative Commons Attribution
Noncommercial License”, enabling the unrestricted non-commercial use, distribution, and reproduction of the
published article in any medium, provided that the original work is properly cited. If the manuscript contains a figure or
table reproduced from a book or another journal article, the authors should obtain permission from the copyright holder
before submitting the manuscript, and be fully responsible for any legal and/or financial consequences if such
permissions are not obtained.
All PDF, XML and html files for all articles published in this journal are the property of the publisher, e-Century
Publishing Corporation (www.e-Century.org). Authors and readers are granted the right to freely use these files for all
academic purposes. By publishing paper in this journal, the authors grant the permanent right to the publisher to use
any articles published in this journal without any restriction including, but not limited to academic and/or commercial
purposes. If you are interested in using PDF, html, XML files or any art works published in this journal for any
commercial purposes, please contact the publisher at business@e-century.org.
Use of Human Subjects/Human Tissue and/or Animal Policy
Experiments involving human subjects should be done in accordance with the relevant ethical and legal standards
established and accepted by their host institution or in accordance with the Helsinki Declaration of 1975, or the
Guidelines of Office for Human Research Protections (OHRP) Human Subject Protections or equivalent. For studies
that involved human subjects, when informed consent has been obtained it should be indicated in the manuscript.
Experiments involving animals should follow the appropriate institution or the National Research Council Guide for the
care and use of laboratory animals.
Units and Abbreviations
System International (SI) units should be used for all measurements. All abbreviations should be explicitly defined at
their first occurrence except for those internationally acceptable. Abbreviations used in the genetic association reports
will need to follow the conventions detailed in the specific information requirements for genetic association reports. Any
articles that involve the description of enzymes will require the inclusion of the appropriate EC (Enzyme Commission)
number as recommended by the Nomenclature Committee of the International Union of Biochemistry and Molecular
Biology (IUBMB).
Disclaimer
While the advice and information in the article are believed to be true and accurate on the date of its going to press,
neither the authors nor the editors can accept any legal responsibilities for any errors or omissions that may be made.
The publication makes no warranty, expressed or implied, with respect to the materials contained within.
PREPARATION OF MANUSCRIPT
All manuscripts should be written in standard grammatical English using computer software (Franklin Gothic Book
normal font, size 12, with single spacing between lines) and should be saved as single DOC (Word) file. Main
Research Articles and Brief Communications will follow a similar format as outlined below while Review Articles will
follow a variation on this (see below).
Main Research Articles are defined as being a substantial novel research study discussing the investigation of a clear
hypothesis or research question with appropriate methodologies (the use of more than one approach is encouraged)
and adequately powered studies and sample sizes. Noting the relevant sections (see below) there is no word limit on
manuscripts of this type except for the Abstract which should be a single unreferenced paragraph and no more than
350 words. There are no limits on the number of display items (tables and/or figures) although authors should try to be
concise and only include the most pertinent information. There are no supplementary tables or figures and every effort
should be made to include these in the main manuscript or alternatively reference should be made in the appropriate
locations of the manuscripts that such information will be available on request from the
corresponding authors. There is no limit on the number of references.
Brief Communications are a format that accommodates the reporting of high quality completed smaller scale studies.
This format is not for the reporting of preliminary or incomplete findings and the review process is equally rigorous as
that for Main Articles. The sections of a Brief Communication follow those of Main Articles (see below) and there should
not be additional sub-headings within these sections.
Review articles have a flexible format, are not of restricted length or reference number. Submissions of reviews must
follow that of Main Research Articles (see below) with the exception that appropriate headings be included for the main
text of the manuscript.
Layout requirements for submissions of Main Research Articles or Brief Communications:
1. cover letter
2. title page
3. abstract and keywords
4. main text
5. acknowledgements, if any
6 Declaration of conflicts of interest, if any
7. References
8. tables, if any
9. figure legends, if any
10. figures, if any
Cover Letter
The cover letter should include name, degree, address, telephone, fax and email of the corresponding author. A
statement that all authors have contributed to, read and approved the final manuscript for submission should be
included if there are multiple authors. Any editorial or financial conflict of interest (e.g., consultancy, stock ownership,
equity interests, patent or licensing agreements) should be clearly disclosed in the cover letter. The disclosure
statement must be submitted upon the acceptance. The cover letter should also be used to provide up the relevant
details of 4 potential reviewers and 2 non-reviewers for your manuscript giving appropriate explanations for the latter.
Finally, if this submission is following the solicitation or invitation of an Editorial Board member please state by whom.
Title Page
1. a concise title;
2. first name, middle initial, and last name of each author;
3. name of the department and institutional affiliation of each author.
4. the email address of each author.(*)
5. a running title.
(*) AJND will only use the email address of the designated corresponding author in the final published manuscript but
will use all email addresses supplied to copy in all authors as additional email respondents to the correspondences
we routinely send to acknowledge receipt of manuscripts, and final decisions made on submitted manuscripts. AJND
would also like, unless otherwise directed in the manuscript covering letter, to use these contact details to announce
the contents lists of future issues of AJND and its sister journals! At no stage will AJND sell such email lists to parties
external to the e-Century Publishing Corporation.
Abstract and Key Words
Abstract should not exceed 350 words that concisely summarize the study’s purpose, significant findings and
conclusions. Include up to 10 key words or phrases at the end of the abstract.
Main Text
The main text should include Introduction, Materials and Methods, Results and Discussion. The Introduction should be
succinct, clearly stating the purpose and rationale of the study. In Materials and Methods, the procedures should be
described in sufficient detail to allow duplication by an independent observer. Results and Discussion should be
divided. They should be written concisely and logically with emphasis on novel findings and minimal repetition of text.
For genetic association reports refer to specific information requirements.
Acknowledgements
All acknowledgements (if any) should be included at the end of the main text before references and may include grant
and administrative support.
References (Please download EndNote X Style or Reference Manager Output Style for AJND)
Reference published in AJND should begin on a new page, be single-spaced and numbered in order of citation in the
text, including citations in tables and figure legends. Complete author citation is required (use of "et al" is not
acceptable). References should conform to the style of the Journal. Examples follow:
Journals: [1] Yin M, Hu Z, Tan D, Ajani JA, Wei Q. Molecular epidemiology of genetic susceptibility to gastric cancer:
focus on single nucleotide polymorphisms in gastric carcinogenesis. Am J Transl Res 2009;1:44-54.
Books: Fishman AP: Pulmonary Hypertension and Cor Pulmonale. Pulmonary Diseases and Disorders. Edited by
Fishman AP. New York, McGraw-Hill, 1988, pp. 999-1048
Web sites: Cite in text only using the appropriate URL. It is the author’s responsibility at the time of submission and
subsequent publication that the website address is relevant and functional.
In press: To be used only for papers accepted for publication. Cite as for journal with (in press) in place of volume and
page numbers.
Personal Communications: to be used very sparingly and in the context of no more than one sentence of associated
text.
Submitted papers/unpublished data: Cite in text only.
Tables
All tables should be created with Microsoft Word Insert Table function, single spacing between rows and cited
consecutively in the main text by Arabic numbers (Table 1, Table 2, etc) and submitted as editable Word file. Include
each table with a descriptive title on a separate page after the references. Provide explanations for any nonstandard
abbreviations in footnotes to the table.
All tables should be included in the Word File as the part of the complete manuscript after bibliography. Tables in
image or other formats are not acceptable. Authors are encouraged to split extremely large tables into multiple smaller
ones to facilitate publication and easiness to readers.
Figure Legends
Figure legends including figure number, a short title and detailed description should be embedded at the end of text
file.
Figures
All figures should be cited consecutively in the main text by Arabic numbers (Figure 1, Figure 2, etc). All figures must be
submitted in TIFF or JPEG format as separate files labeled with the corresponding numbers. Photographs of a person
should render them unidentifiable or include their written permission. Any figures involving Copyright issues should
conform to the Copyright policy.
Publication Fees
American Journal of Neurodegenerative Disease is an open access journal which provides instant, worldwide and
barrier-free access to the full-text of all published articles. Publication charges allow the publisher to make the
published material available for free to all interested online readers.
The Publishing fee is $980 per article. This will be billed to the corresponding author. There is no extra charge for color
figures. Authors who do not have appropriate funds from developing countries can apply to have the reduced fee by
submitting a letter signed by the departmental chair to state such a fact. Editorial decisions are not contingent upon the
ability to pay publication charges.