AJND Copyright © Since 2012-All rights reserved. Published by e-Century Publishing Corporation, Madison, WI 53711, USA
Information for Authors

American Journal of Neurodegenerative Disease (AJND, ISSN: 2165-591X) is an open access online journal
dedicated to rapid publication of basic and clinical research findings in neurodegenerative diseases including, but not
limited to Alzheimer’s Disease (AD), Parkinson’s Disease (PD), corticobasal degeneration, progressive supranuclear
palsy (PSP), Pick's disease, and frontotemporal dementia (FTD), etc. The scope of AJND encompasses all areas of
neurodegenerative disease. AJND welcomes original and review articles on both clinical investigation and basic
research. Occasionally, special topic issues, short communications, editorials, and invited perspectives will also be
published. Manuscripts, including figures and tables, must be original and not under consideration by another journal.

SUBMISSION OF MANUSCRIPT (Click to submit manuscript)


Authors’ responsibilities

To ensure that submitted manuscripts have not been published elsewhere (except in the form of an abstract or as part
of a published lecture or thesis) and are not currently under consideration for publication by another journal.

To ensure all authors have contributed to, read and approved the final manuscript for submission.

To ensure that all data in the submitted manuscript are authentic. Maintain accurate records of data associated with
their submitted manuscript and to provide this data upon reasonable request.

To inform the editor of any other submitted manuscripts that might contain overlapping or closely related content.

To obtain permission to reproduce any content from other sources.

To confirm that all the work in the submitted manuscript is original, and to acknowledge and cite any content
reproduced from other sources.

To ensure that any studies involving human or animal subjects conform to national, local and institutional laws and
requirements (e.g. WMA Declaration of Helsinki, the Guidelines of Office for Human Research Protections (OHRP)
Human Subject Protections, NIH Policy on Use of Laboratory Animals, or equivalent). For studies involving human
subjects, authors should obtain express permission from subjects and respect their privacy. Confirmation that
approval has been sought and obtained should be included in the manuscript where applicable. Experiments involving
animals should follow the appropriate institution or the National Research Council Guide for the care and use of
laboratory animals.

Declare any potential conflicts of interest that could be perceived as exerting an undue influence on his or her duties at
any stage during the publication process.

To notify promptly the journal editor or publisher if a significant error in their publication is identified, and to cooperate
with the editor and publisher to provide retractions or corrections if necessary.
Keep a copy of the manuscript submitted in case of revision, rejection, loss or damage. Receipt of manuscripts will be
acknowledged and a decision regarding acceptance made as soon as possible. Accepted manuscripts may be
subject to editorial revision without notice.

Authors should provide 4 potential peer reviewers with detailed contact information including e-mail address. Authors
may also nominate 2 peers that they request are not sent the article for peer review for conflicts of interest or other
appropriate reasons – in such instances some reasonable justification must be given. These should be experts in
their field of study, who will be able to provide an objective assessment of the manuscript. If not provided, potential
reviewers will be identified by their publication record or recommended by the Editorial Board members. All
manuscripts are subject to peer review and are expected to meet the rigorous standards of academic excellence.

Reviewers’ responsibilities

To ensure that accepted manuscripts meet the rigorous standards of academic excellence.

To review submitted manuscripts objectively, and in a timely manner.
To maintain the confidentiality of any information supplied by the editor or author, and to not retain or copy the
manuscript in any manner.

To alert the editor of any published or previously submitted content that is substantially similar to that under review.

To point out any relevant published work that is not yet cited.

To be aware of any potential conflicts of interest between the reviewer and author/research funders(financial,
institutional, collaborative or otherwise). To alert the editor to any potential conflicts of interest and if necessary,
withdrawing their services for that manuscript.

Editors’ responsibilities

To act in a balanced, fair and objective way while carrying out duties without discrimination based on sexual
orientation, religious or political beliefs, gender, ethnic or geographical background of the authors. Editors have
complete responsibility and authority to accept and/or reject manuscripts.

Ensure that there is no conflict of interest with respect to manuscripts they reject/accept.

To ensure that all manuscripts, including submissions for sponsored supplements or special issues are handled in
the same way as other submissions, so that articles are considered and accepted solely on their academic merit
without any commercial influence.

To preserve the anonymity of reviewers.

To adopt and follow reasonable procedures in the event of any complaints, ethical or otherwise, in accordance with the
policies and procedures of COPE (www.publicationethics.org). To give authors a reasonable opportunity to respond to
any complaints. All complaints should be investigated no matter when the original publication was approved, and
documentation associated with any such complaints should be retained.

To promote the publication of corrections and/or retractions when errors are found.

Publisher Responsibilities

To ensure that all articles published meet the standards and requirements outlined above.

To ensure that any corrections, retractions, and/or clarifications are published when necessary.

To maintain the integrity of the academic record, and preclude business needs from compromising intellectual and
ethical standards.

Identification of Unethical Behavior

Misconduct and/or unethical behavior may be identified and brought to the attention of the editor and publisher at any
time, by anyone.

Whoever informs the editor or publisher of misconduct should gather sufficient evidence and information in order for an
investigation to be initiated. Evidence should be gathered in a discreet manner, in order to avoid spreading allegations
beyond those who absolutely need to know, in order to protect the confidentiality of the parties in question until a
conclusion has been reached.

All allegations will be taken seriously and handled in the same manner.

The editor will take initial action, with additional input from the publisher where appropriate.

In every case, authors will be given the opportunity to respond to any allegations.

Misconduct and Possible Outcomes

Minor breaches of conduct might be dealt with internally, without the need for any outside consultation;

Depending on the severity of the infraction, other outcomes may include, but are not limited to the following:
Informing the author or reviewer of the infraction, and educating him/her   on how to avoid future breaches of conduct;
A written warning regarding the breach of conduct;
Publication of a formal notice and/or editorial detailing the misconduct;

A formal letter to the author’s department head and/or funding agency;

Retraction of the publication from the journal, and informing both the  Abstracting & Indexing services as well as the
readership of the publication of the infraction;

Suspension of the author’s eligibility for publication;

Reporting the breach of conduct to a higher authority for further investigation and action.

Copyright Policy

By submitting a manuscript to any of e-Century Publishing Corporation journal, all authors agree that all
copyrights of all materials included in the submitted manuscript will be exclusively transferred to the publisher, e-
Century Publishing Corporation once the manuscript is accepted.

Once the paper is published, the copyright will be released by the publisher under the “Creative Commons Attribution
Noncommercial License”, enabling the unrestricted non-commercial use, distribution, and reproduction of the
published article in any medium, provided that the original work is properly cited.
If the manuscript contains a figure
or table reproduced from a book or another journal article, the authors should obtain permission from the
copyright holder before submitting the manuscript,
and be fully responsible for any legal and/or financial
consequences if such permissions are not obtained.

All PDF, XML and html files for all articles published in this journal are the property of the publisher, e-Century
Publishing Corporation (
www.e-Century.org). Authors and readers are granted the right to freely use these files for all
academic purposes. In addition,
the author has the right to reuse any materials in his/her own paper for any
purpose without getting the permission from the publisher
provided that the original work is properly cited.By
publishing paper in this journal, the authors grant the permanent right to the publisher to use any articles published in
this journal without any restriction including, but not limited to academic and/or commercial purposes.

If you are interested in using PDF, html, XML files or any art works published in this journal for
any commercial
, please contact the publisher at business@e-century.org.

Units and Abbreviations

System International (SI) units should be used for all measurements. All abbreviations should be explicitly defined at
their first occurrence except for those internationally acceptable. Abbreviations used in the genetic association reports
will need to follow the conventions detailed in the specific information requirements for genetic association reports. Any
articles that involve the description of enzymes will require the inclusion of the appropriate EC (Enzyme Commission)
number as recommended by the Nomenclature Committee of the International Union of Biochemistry and Molecular
Biology (IUBMB).


While the advice and information in the article are believed to be true and accurate on the date of its going to press,
neither the authors nor the editors can accept any legal responsibilities for any errors or omissions that may be made.
The publication makes no warranty, expressed or implied, with respect to the materials contained within.

PREPARATION OF MANUSCRIPT (Download Sample Manuscript)

All manuscripts should be written in standard grammatical English using computer software (Arial normal font, size 12,
with single spacing between lines) and should be saved as single DOC (Word) file. Main Research Articles and Brief
Communications will follow a similar format as outlined below while Review Articles will follow a variation on this (see

Main Research Articles are defined as being a substantial novel research study discussing the investigation of a clear
hypothesis or research question with appropriate methodologies (the use of more than one approach is encouraged)
and adequately powered studies and sample sizes. Noting the relevant sections (see below) there is no word limit on
manuscripts of this type except for the Abstract which should be a single unreferenced paragraph and no more than
350 words. There are no limits on the number of display items (tables and/or figures) although authors should try to be
concise and only include the most pertinent information. There are no supplementary tables or figures and every effort
should be made to include these in the main manuscript or alternatively reference should be made in the appropriate
locations of the manuscripts that such information will be available on request from the
corresponding authors. There is no limit on the number of references.

Brief Communications are a format that accommodates the reporting of high quality completed smaller scale studies.
This format is not for the reporting of preliminary or incomplete findings and the review process is equally rigorous as
that for Main Articles. The sections of a Brief Communication follow those of Main Articles (see below) and there should
not be additional sub-headings within these sections.

Review articles have a flexible format, are not of restricted length or reference number. Submissions of reviews must
follow that of Main Research Articles (see below) with the exception that appropriate headings be included for the main
text of the manuscript.

Layout requirements for submissions of Main Research Articles or Brief Communications:

1.        cover letter
2.        title page
3.        abstract and keywords
4.        main text
5.        acknowledgements, if any
6         Disclosure of conflicts of interest, if any
7.        References
8.        tables, if any
9.        figure legends, if any
10.      figures, if any

Cover Letter

The cover letter should include name, degree, address, telephone, fax and email of the corresponding author. A
statement that all authors have contributed to, read and approved the final manuscript for submission should be
included if there are multiple authors. Any editorial or financial conflict of interest (e.g., consultancy, stock ownership,
equity interests, patent or licensing agreements) should be clearly disclosed in the cover letter. The disclosure
statement must be submitted upon the acceptance. The cover letter should also be used to provide up the relevant
details of 4 potential reviewers and 2 non-reviewers for your manuscript giving appropriate explanations for the latter.
Finally, if this submission is following the solicitation or invitation of an Editorial Board member please state by whom.

Title Page

1.        a concise title;
2.        first name, middle initial, and last name of each author;
3.        name of the department and institutional affiliation of each author.
4.        the email address of each author.(*)
5.        a running title.

(*) AJND will only use the email address of the designated corresponding author in the final published manuscript but
will use all email addresses supplied to copy in all authors as additional email respondents to the correspondences
we routinely send to acknowledge receipt of manuscripts, and final decisions made on submitted manuscripts. AJND
would also like, unless otherwise directed in the manuscript covering letter, to use these contact details to announce
the contents lists of future issues of AJND and its sister journals! At no stage will AJND sell such email lists to parties
external to the e-Century Publishing Corporation.

Abstract and Key Words

Abstract should not exceed 350 words that concisely summarize the study’s purpose, significant findings and
conclusions. Include up to 10 key words or phrases at the end of the abstract.

Main Text

The main text should include Introduction, Materials and Methods, Results and Discussion. The Introduction should be
succinct, clearly stating the purpose and rationale of the study. In Materials and Methods, the procedures should be
described in sufficient detail to allow duplication by an independent observer. Results and Discussion should be
divided. They should be written concisely and logically with emphasis on novel findings and minimal repetition of text.
For genetic association reports refer to specific information requirements.


All acknowledgements (if any) should be included at the end of the main text before references and may include grant
and administrative support.

References (Please download
EndNote X Style or Reference Manager Output Style for AJND)

Reference published in AJND should begin on a new page, be single-spaced and numbered in order of citation in the
text, including citations in tables and figure legends. Complete author citation is required (use of "et al" is not
acceptable). References should conform to the style of the Journal. Examples follow:

Journals: [1]  Yin M, Hu Z, Tan D, Ajani JA, Wei Q. Molecular epidemiology of genetic susceptibility to gastric cancer:
focus on single nucleotide polymorphisms in gastric carcinogenesis. Am J Transl Res 2009;1:44-54.

Books: Fishman AP: Pulmonary Hypertension and Cor Pulmonale. Pulmonary Diseases and Disorders. Edited by
Fishman AP. New York, McGraw-Hill, 1988, pp. 999-1048

Web sites: Cite in text only using the appropriate URL. It is the author’s responsibility at the time of submission and
subsequent publication that the website address is relevant and functional.

In press: To be used only for papers accepted for publication. Cite as for journal with (in press) in place of volume and
page numbers.

Personal Communications: to be used very sparingly and in the context of no more than one sentence of associated

Submitted papers/unpublished data: Cite in text only.


All tables should be created with Microsoft Word Insert Table function, single spacing between rows and cited
consecutively in the main text by Arabic numbers (Table 1, Table 2, etc) and submitted as editable Word file. Include
each table with a descriptive title on a separate page after the references. Provide explanations for any nonstandard
abbreviations in footnotes to the table.

All tables should be included in the Word File as the part of the complete manuscript after bibliography. Tables in
image or other formats are not acceptable. Authors are encouraged to split extremely large tables into multiple smaller
ones to facilitate publication and easiness to readers.

Figure Legends

Figure legends including figure number, a short title and detailed description should be embedded at the end of text


All figures should be cited consecutively in the main text by Arabic numbers (Figure 1, Figure 2, etc). All figures must be
in high quality, inserted at the end of the Word file of the manuscript and labeled with the corresponding numbers. The
text in all figures must be in Arial font. Photographs of a person should render them unidentifiable or include their
written permission. Any figures involving Copyright issues should conform to the Copyright policy.

Publication Fees

American Journal of Neurodegenerative Disease is an open access journal which provides instant, worldwide and
barrier-free access to the full-text of all published articles. Publication charges allow the publisher to make the
published material available for free to all interested online readers.

The Publishing fee is $1180 per article. This will be billed to the corresponding author. There is no extra charge for
color figures.

Submit Manuscript

All manuscript must be submitted online. Please visit Checking List and then submit your manuscript.